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MDMA (3,4-Methylenedioxymethamphetamine) works by affecting the brain’s chemistry, specifically the levels and activity of certain neurotransmitters. Here’s a simplified explanation:
- Serotonin release: MDMA triggers the release of serotonin, a neurotransmitter associated with feelings of happiness, relaxation, and empathy.
- Dopamine release: MDMA also releases dopamine, a neurotransmitter linked to pleasure, reward, and motivation.
- Norepinephrine release: Additionally, MDMA releases norepinephrine, a neurotransmitter involved in attention, arousal, and energy.
- Reuptake inhibition: MDMA blocks the reabsorption (reuptake) of these neurotransmitters, allowing them to accumulate in the synaptic cleft (the gap between neurons).
- Binding to receptors: The increased levels of serotonin, dopamine, and norepinephrine bind to their respective receptors, activating neural pathways and producing the characteristic effects of MDMA.
The effects of MDMA are divided into three phases:
- Onset (30 minutes to 1 hour): Users may feel a sense of excitement, euphoria, and increased energy.
- Plateau (2-4 hours): The peak effects of MDMA, including feelings of empathy, relaxation, and altered perception.
- Comedown (2-4 hours): As the drug is metabolize and eliminate,
- users may experience a gradual return to normal, accompany by fatigue, irritability, or depression.
Keep in mind that individual experiences may vary,
and the effects of MDMA can be influence by factors like dose, setting, and individual tolerance.
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